According to the World Health Organization (WHO), in addition to serious illness and death, the panel considers the need to develop drugs against COV-19, which have a greater impact on the prevention of infection and transmission.
In the current context of the spread of Omicron, the text states that until such vaccines become available, and when the corona virus develops, it is necessary to update the composition of the immunogens and ensure that they continue to provide a level of protection.
To that end, the document states that immunogens against Covit-19 should be based on mutations that are genetically and antigenically close to the cyclical changes of SARS-CoV-2.
In addition to protecting against serious illness and death, they should be very effective in protecting against infections, thus reducing community outbreaks and requiring drastic social and public health measures.
They should exhibit broad, strong, and long-lasting immune responses to reduce the need for continuous booster doses.
To achieve these types of products, the team encourages vaccine manufacturers to generate and provide data on their effectiveness against Omicron, including the persistence of humorous and cell-mediated immune responses to variations through monovalent vaccines and / or multivalent.
“The challenge of ensuring the timely production of the best vaccines possible requires continuous communication and cooperation between the WHO, its expert groups, regulatory authorities and manufacturers,” the statement said.
He further points out that with the vaccines available today, the current focus is on reducing serious diseases and deaths and protecting health systems.
The International Organization reaffirms that “these types of products, approved by the WHO for emergency use, provide a high level of protection against serious illness and death on a variety of platforms.”
Similarly, it highlights the importance of emergency, broad and equitable approaches to provide greater protection and mitigate the emergence of new species by reducing the burden of infections.
Gas / CDG